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It was also observed that the
2018-11-02
It was also observed that the expression of Nestin, Hes1 and Sox2 in CDr3Bright adult sorted cells were lower than the unsorted fraction or largely unchanged. Studies have shown that it is likely that multiple classes of neural stem/progenitor cells exist, each classified by distinct gene expression
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Although GPX is known as a gastrointestinal GSH peroxidase i
2018-11-02
Although GPX2 is known as a gastrointestinal GSH peroxidase, it also is expressed in other tissues (Brigelius-Flohé and Kipp, 2012). Interestingly, its expression level is increased in intestinal crypt stem cells and malignant epithelial cells, suggesting a role in proliferation and self-renewal. It
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Meanwhile in vitro studies of neural induction from hPSCs
2018-11-02
Meanwhile, in vitro studies of neural induction from hPSCs have suggested that radial arrangements of columnar neuroepithelial cells, termed neural rosettes, can differentiate toward peripheral nervous system (PNS) lineages (Chambers et al., 2009; Kim et al., 2010) and reported evidence of neural cr
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There are multiple ways whereby oxidative stress may
2018-11-02
There are multiple ways whereby oxidative stress may promote FOXO activation. For example, FOXO proteins can directly sense ROS through the ability of ROS to induce disulfide bridges between cysteine residues on the FOXO protein, resulting in FOXO activation and transcription of ROS-removal calcium
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We previously identified a minimal surface phenotype
2018-11-02
We previously identified a minimal surface phenotype suited not only to enrich the archetypal human “MSCs” in uncultured BM cell suspensions, but also to correlate their ex vivo-assayed clonogenic capacity with their in situ identity and in vivo fate following transplantation (Sacchetti et al., 2007
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br Experimental Procedures br Author
2018-11-02
Experimental Procedures Author Contributions Acknowledgments We thank Drs. Shinichi Aizawa and Frank Costantini for providing mice, and Yuuki Honda, Mayumi Yamamoto, Nanako Goto, Chiaki Kaieda, Masato Tanaka, and Kanako Motomura for excellent technical assistance. This work was supported in
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br Experimental Procedures br Author Contributions br Acknow
2018-11-02
Experimental Procedures Author Contributions Acknowledgments This work is supported by national Portuguese funding through FCT, Fundação para a Ciência e a Tecnologia, project UID/BIM/04773/2013 CBMR, projects PEst-OE/EQB/LA0023/2013 and PTDC/SAU-ENB/111702/2009 to J.B., U01HL100408, NIH/NH
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The systematic uncertainty of measurements was estimated as
2018-11-02
The systematic uncertainty of measurements was estimated as equal to 7–13% depending on the particle transverse momentum. The main sources of systematic uncertainty are: Experimental results from the ALICE detector Invariant differential production spectra of φ-mesons were measured in p + Pb col
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The goal of this study is to obtain the
2018-11-02
The goal of this study is to obtain the information on the temperature bmn 673 of the magnetic properties of the LSMO-0.07 and LSMO-0.125 compounds in the 4–240K temperature range, i.e., exactly where the unusual macroscopic properties of these materials are observed. The experimental part The
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topotecan Supplier It is important for sorption enhanced cat
2018-11-02
It is important for sorption-enhanced catalytic processes occurring in an aqueous medium that the MnО2 phase be in a hydrated state. This requirement imposes certain restrictions on the conditions in which this phase can be synthesized, particularly on the CL surface that is sensitive to acidic and
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Spectral analysis was used to identify
2018-11-02
Spectral analysis was used to identify the segments of the strainmeter recordings where the period coincided with the period during which the transducer operated in the sea. Fig. 3 shows synchronous dynamic spectrograms of the recordings of the complex phase-shift signal by the reference hydrophone
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Persistent light carers group exhibit the best health outcom
2018-11-02
Persistent light carers (group 6) exhibit the best health outcomes (OR 0.45, 95% CI 0.39–0.52). Among light carers at 2001 who were then providing heavy care at 2011 (group 7) and non-carers at 2001 who were light carers at 2011 (group 2), the odds of reporting poor health at 2011 are identical (OR
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There were countries for which we had iAD
2018-11-02
There were 58 countries for which we had iAD data and for which the UN database provided information about the rate of adult literacy. When these variables were simply correlated (see the Appendix for a table of simple correlations among all the measures mentioned in Methods section), a significant
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tazarotene With similarities and differences in social econo
2018-11-02
With similarities and differences in social, economic, and political contexts in Canada and the United States, it tazarotene has been suggested that comparing these two countries holds important insights for understanding how structural determinants, such as social policies and economic resources,
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br Conclusions br Conflict of interest
2018-11-02
Conclusions Conflict of interest Acknowledgements: This work was funded by FORTE (Swedish Research Council for Health, Working Life and Welfare; Grant numbers 2013-1269 and 2012-0979), and the Medical Faculty at Lund University. These institutions had no involvement regarding the collection
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