• It is established that hypoxia can induce autophagy

  2019-04-29

  

  It is established that hypoxia can induce autophagy [32,34–37]. We evidenced the autophagic activation in the cultured human osteosarcoma MG-63 neomycin sulfate after incubation in 1% O2 for 24h. The concomitantly elevated LC3 protein levels with HIF-1α high expression on OS tissue sections also in

• Yet could it be that the IMF had contributed to

  2019-04-29

  

  Yet, could it be that the IMF had contributed to the circumstances that enabled the crisis to arise in the first place? A major reason why the outbreak spread so rapidly was the weakness of health systems in the region. There were many reasons for this, including the legacy of conflict and state fai

• br Potential therapeutic use of PI

  2019-04-29

  

  Potential therapeutic use of PI3Kα and/or pan-PI3K inhibitors in CLL PI3Kδ has been the overwhelming target of choice for PI3K inhibition in CLL; however there is mounting evidence for important roles of other PI3K isoforms in CLL and of functional redundancy between PI3K isoforms in leucocytes i

• The slow progress towards combating health inequalities migh

  2019-04-29

  

  The slow progress towards combating health inequalities might be because of the poor approach to understanding and acting on the social determinants of health. Responsibilities for health in the global arena go beyond a country\'s Ministry of Health and WHO. Health beyond health is the concept that

• The following dataset was collected for each participant age

  2019-04-29

  

  The following dataset was collected for each participant: age ( 6 years), sex, medical diagnosis, caries status, types and numbers of treatments, and any complications. Caries status was recorded based on the World Health Organization oral health survey criteria and methods, which use the decayed, e

• Pneumonitis has been reported after TLI in

  2019-04-28

  

  Pneumonitis has been reported after TLI in Ewing\'s sarcoma [21], but no serious toxicity like we reported in these two patients has previously been presented [1,6,7]. The radiation treatments in our patients were audited internally at our institution, but no abnormalities found. When retrospective

• orexin agonist Las de Am rica Latina constituyen el tormento

  2019-04-28

  

  Las de América Latina constituyen el tormentosa diríamos, del libro. Es importante citar textualmente, en palabras del editor del volumen, lo que implica este revelador membrete: Entre los variados frutos que ha producido el proyecto de investigación “Interacción de los exilios de México e Iber

• br Discussion Intriguingly in a case report about elevation

  2019-04-28

  

  Discussion Intriguingly, in a case report about elevation of skeletal enzymes in ultramarathon runners, the CK level reached its peak value one day after the run, had a ∼4-day plateau, and began to decline after a few more days. The sustained increase of plasma CK in this athlete was quite differ

• The management of PEComa follows the same treatment principl

  2019-04-28

  

  The management of PEComa follows the same treatment principles as other subtypes of soft tissue sarcoma. Surgical resection remains the primary treatment modality. There is no consensus on the administration of adjuvant treatment. Other treatment options, including chemotherapy and radiotherapy, hav

• br Introduction Bone marrow adipocytes are one of

  2019-04-28

  

  Introduction Bone marrow adipocytes are one of the most abundant cell types found in bone marrow tissue. They constitute approximately 15% of the bone marrow volume in young adults, rising to 60% by the age of 65 years old [1]. Previously considered as inert space filling cells with little biolog

• br Material and methods br Results

  2019-04-28

  

  Material and methods Results Discussion Conclusions Conflict of interest Introduction Scoliosis forms a complex curve in all three planes, not only in the coronal plane, leading to deformities caused by the self-rotating movement of the spine [1]. Spinal anomalies may impair cardio

• In Telek Ayove and colleagues report a comparison of the

  2019-04-28

  

  In , Telek Ayove and colleagues report a comparison of the Dual Path Platform (DPP) Syphilis Screen and Confirm test (Chembio Diagnostic Systems, Medford, NY, USA) with non-treponemal (RPR) and treponemal (TPHA) serological tests for diagnosis of yaws in two remote communities in Papua New Guinea wi

• The median standardised inclusion score for the countries re

  2019-04-28

  

  The median standardised inclusion score for the 70 countries reviewed was 1·53 (IQR 0·63–2·09), corresponding to a reasonable level of inclusion. Countries showing best practice (score of 4) were Moldova, Ghana, Serbia, and the Dominican Republic. 20 countries (29%) showed strong inclusion, 25 count

• Con Lemebel y Perlongher y la resonancia que en ellos

  2019-04-28

  

  Con Lemebel y Perlongher, y la resonancia que en ellos tienen Gilíes Deleuze y Félix Guattari, puede percibirse un gesto de queeridad sudamericano, un “infinito devenir minoritario, nómade, siempre en movimiento, en el que podemos leer la emergencia de una mirada que se acerca axl inhibitor lo queer

• National coverage trends were accelerated

  2019-04-26

  

  National coverage trends were accelerated because of the contribution of trends in the two poorest quintiles. In middle-income countries, for example, the estimated increase in national trends was around 25% faster as a result of the contribution of poor populations. Increases in coverage in rural a

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