• br Introduction Sepsis is a life

  2018-10-23

  

  Introduction Sepsis is a life-threatening syndrome commonly experienced by patients in critical care units. Sepsis syndrome poses a particular concern for people with prior health conditions, a phenomenon often referred as “second-hit” or “pre-conditioning” (Rocksen et al., 2004; Wang et al., 199

• br Introduction Although the incidence of

  2018-10-23

  

  Introduction Although the incidence of HIV has peaked in much of sub-Saharan Africa, the tuberculosis (TB) epidemic continues unabated with TB remaining the leading cause of death in those living with HIV (World Health Organization, 2014). While many studies have investigated the impact of HIV in

• br Contributors br Declaration of Interests br Acknowledgmen

  2018-10-23

  

  Contributors Declaration of Interests Acknowledgments This investigation received financial support from the Agencia Nacional de Promoción Científica y Tecnológica (ANPCyT, PAE-PID-00127, PAE-PICT-207-02332 and PICT-0240 to VEG); University of Buenos Aires (20020100100221 and 20020130100236

• The levels of LRG have been shown to be

  2018-10-23

  

  The levels of LRG1 have been shown to be elevated in the serum and urinary exosomes of lung cancer patients (Li et al., 2011; Liu et al., 2012) with this protein also being identified in lung tumour tissue. The role of LRG1 is not fully understood, although it is of interest due to its role in angio

• br Methods br Results Changes in life

  2018-10-23

  

  2. Methods 3. Results Changes in life expectancy associated with the two screening strategies (one-time and annual screening) across all study cohorts apoptosis pathway included in Table 2. One-time screening at age 50 for the primary cohort resulted in a LE gain of 3.9days. One-time screening

• The goal of organ on a chip

  2018-10-23

  

  The goal of organ-on-a-chip devices is to recapitulate tissue- and organ-level functions in a simple, yet easily manipulated apparatus. The simplest systems involve the growth of one or more cell types in a single, perfused microfluidic chamber to exhibit the functions of one tissue type. More compl

• Collectively these findings suggest a role for ST

  2018-10-23

  

  Collectively, these findings suggest a role for ST2 in HIV pathogenesis; this process is probably driven by HIV-induced damage to gut epithelial Dihydromyricetin manufacturer during the early, asymptomatic phase of infection. These findings also suggest that ST2 might be used as a surrogate marker

• br Conclusion br Author Contributions br Competing Financial

  2018-10-23

  

  Conclusion Author Contributions Competing Financial Interests Acknowledgement This study was supported by Research Grant Council General Research Fund (HKU-17613815) to Tatia M.C. Lee. The funding agency has no roles in study design, data collection, data analysis, finding interpretation

• br Conflicts of Interest br

  2018-10-23

  

  Conflicts of Interest Authors\' Contributions Funding Introduction Vaso-occlusive crisis (VOC), hallmark of sickle-cell disease (SCD), is the primary cause of Emergency-Department admissions and patients\' hospitalizations (Ballas and Lusardi, 2005). About 20% of all-age deaths in the Un

• This study is important because our ability to

  2018-10-23

  

  This study is important because our ability to identify enough SNPs for a risk profile for clinical implementation is dependent on combining multiple heterogeneous cohorts. The aim was to show that multi-center radiotherapy cohorts could be harmonized and analyzed to identify risk SNPs by increasing

• br Conflicts of Interest br Author Contributions br Acknowle

  2018-10-23

  

  Conflicts of Interest Author Contributions Acknowledgements Introduction Hepatitis C virus (HCV) is a major global public health problem. Although HCV incidence is declining, morbidity and mortality related to chronic HCV infection are increasing (Aspinall et al., 2015; Kuo et al., 2015)

• An important finding in our recent study

  2018-10-23

  

  An important finding in our recent study was that prostate cancer could be divided into five distinct molecular subgroups based on stratification with a small number of copy number features which were also associated with RNA-expression change. These groups had different clinical outcomes. We wanted

• In a previous study we firstly uncovered

  2018-10-23

  

  In a previous study, we firstly uncovered the crucial role of NFAT5 in the development of autoimmune disease by demonstrating that NFAT5-deficient mice showed a marked corticotropin releasing factor of antibody-induced arthritis (Yoon et al., 2011). Moreover, we have demonstrated that NFAT5 is highl

• Although still incurable the survival rate of MM

  2018-10-23

  

  Although still incurable, the survival rate of MM, the second most common hematologic malignancy (Siegel et al., 2014), has improved mainly due to the development of new and highly effective agents, such as immunomodulators and proteasome inhibitors (Kumar et al., 2012). CFZ is an irreversible epoxy

• The following are the supplementary data related

  2018-10-23

  

  The following are the supplementary data related to this article. Conflict of Interest Author Contributions Introduction Microarray-based gene profiling studies of breast tumors validated that breast cancer is a heterogonous disease and can be sub-classified into different subtypes exhibit

15254 records 1014/1017 page Previous Next First page 上5页 10111012101310141015 下5页 Last page