• The same proof of concept study however revealed that the

  2018-11-05

  

  The same proof-of-concept study however, revealed that the retrospective application of standardized case criteria will result in a certain amount of missing data and indeterminate results with regard to the case definitions. This was the case whenever critical data that would be required for the ca

• Increased neuronal activation could lead to cellular swellin

  2018-11-05

  

  Increased neuronal activation could lead to cellular swelling and also activity-dependent myelin-modulation via increased astrocyte activity (Messina et al., 2015), which could account for the diffusion alterations in our findings. Therefore, one plausible and perhaps most likely explanation for our

• In the nearly years since the

  2018-11-05

  

  In the nearly 18years since the clevidipine investigational new drug application was filed, our understanding of the structure, tissue distribution and molecular biology of the l-type calcium channels (LTCC) has evolved dramatically (Zuccotti et al., 2011; Abernethy and Soldatov, 2002). The CaV-α-1

• br Materials Methods br Results To better understand how ZIK

  2018-11-05

  

  Materials & Methods Results To better understand how ZIKV infection may lead to microcephaly, we developed an assay to infect cultured mouse embryonic hippo signaling slices and tested the ability of ZIKV and other flaviviruses to infect the neocortex (Fig. 1a). We selected an isolate of DENV

• br CRISPR Cas Tips and Tricks Dario

  2018-11-05

  

  CRISPR Cas9 Tips and Tricks Dario Lupianez and Malte Spielmann (Berlin, Germany) held an engaging workshop titled CRISPR Cas9 tips and tricks. The aim was to demonstrate how this genome editing technology can be utilized in embryonic stem Dynasore cost (ESCs) to produce genomic structural variat

• Overall obesity can lead to

  2018-11-05

  

  Overall, obesity can lead to renal functional disorders and induce hypertension through a variety of mechanisms: (Hall, 1997; Hall et al., 1999; Hall et al., 2002; Hall et al., 2010; Hall et al., 2015; Hall et al., 2014). Activation of sympathetic nervous system; Physical–mechanical compression; Ren

• The characteristic technique of optimization involves varyin

  2018-11-05

  

  The characteristic technique of optimization involves varying one variable at a time and keeping the other constant. This method is not only laborious but does not also represent the complete effects of the variables in the process and ignores the combined interactions between the variables (Survase

• br Conclusion br Introduction Platinum group metals

  2018-11-05

  

  Conclusion Introduction Platinum group metals (PGMs) are applied in several different industries, hence the interest in developing methods for their separation (Kolekar and Anuse, 2002). Rhodium, for example, has been in demand in recent years since it is indispensable in automotive catalytic

• br Geological setting Ultramafic mafic nappes

  2018-11-05

  

  Geological setting Ultramafic-mafic nappes, as well as mélange consisting of marble and greenschist facies rocks are exposed along the Nujiang River in the studying area (Figs. 1 and 2). The NW-SE course of the Nujiang River is regarded as an important tectonic boundary, the trace of the Bongong-

• With altitude the saturation values differ

  2018-11-05

  

  With altitude, the saturation values differ, however, the majority of the studies has been performed at more than 3000m. In six normal subjects, the average SaO2 during sleep were of 97.3%, 83.0% and 71.0% measured, respectively at 500m, 4200m, and 6400m [18]. In another study, the saturation at ext

• The electrocardiograph is an electronic device that captures

  2018-11-05

  

  The electrocardiograph is an electronic device that captures and adjusts the heart’s electrical signals for their analysis and study. The electrocardiograph developed in this research is called EKG-3DT (diagnostic electrocardiograph with three bipolar derivations). When the heart beats, many excitab

• br Materials and methods br

  2018-11-05

  

  Materials and methods Results Microfluidic analytical devices with optical detection are considered one of the best options for developing robust and sensitive lab-on-chip devices. Key features for diagnostic and prognostic usefulness of such devices are high sensitivity and specificity, abili

• br Results Response rate of participating pharmacists was

  2018-11-05

  

  Results Response rate of participating pharmacists was 70.6%, i.e., 60 out of 85 approached agreed to participate in the study. Number of packs sold in a month per pharmacy varied from 2 to 500 packs/month, with a mean of 62 packs every month. Thirty‐eight pharmacists claimed that clients took th

• Current voltage I V characterization was conducted using a

  2018-11-03

  

  Current–voltage (I–V) characterization was conducted using a Keithley 2400 source measurement apparatus in a four-wire setup in ambient neurokinin receptor antagonist with an ORIEL solar simulator (class ABA) at AM 1.5G. A silicon reference cell (PV Measurements, Inc. 20mm×20mm) was used for the ca

• br Data CMP experiments were performed on the titanium plate

  2018-11-03

  

  Data CMP experiments were performed on the titanium plates by altering the sample surface through various CMP conditions [1]. First, slurry particle size and stability were evaluated through particle light scattering based particle size measurement by using Coulter LS 13 320 equipment as can be s

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