• br Self organized pattern formation at

  2018-11-08

  

  Self-organized pattern formation at the ‘edge of chaos’ Self-organization is a key concept in theoretical physics that bafilomycin a1 autophagy refers to a state far from thermodynamic equilibrium that arises when microscopic fluctuations are too great for a system to contain (Ball, 2001; Chaiss

• br Author contribution The following are the supplementary

  2018-11-08

  

  Author contribution The following are the supplementary data related to this article. Acknowledgments We thank Catherine Bresse for her valuable assistance in the statistical analysis. This work was supported by the CIRM grant # RL1-00636-1. Introduction The capacity of human embryonic st

• In hematological malignancies cancer initiating cells have b

  2018-11-08

  

  In hematological malignancies, cancer-initiating E-4031 have been identified as a population potentially representing a key clinical target (Matsui et al., 2004; Dick and Lapidot, 2005; Gupta et al., 2009). This paradigm, now extended to some solid cancers, is based on the concept that a single immu

• Ponceau S Staining Solution We have demonstrated also in

  2018-11-08

  

  We have demonstrated also in this study that inhibition of the cellular antioxidant mechanism could promote differentiation of GICs. We also observed that GICs have an enhanced antioxidant mechanism compared to their serum-differentiated counterparts. Based on these findings, we speculate that GICs

• Finally we provide molecular evidence for PB transposase act

  2018-11-08

  

  Finally, we provide molecular evidence for PB transposase activity in vivo after plasmid intramuscular injection and electrotransfer of the murine muscles, for instance from the recovery and sequencing of several transposon–genomic junctions. Interestingly, such integration events were not able to m

• Senexin A br Materials and methods br Results

  2018-11-08

  

  Materials and methods Results There are a number of complex methods for the generation of neural subtypes from hESCs and iPSCs. In most of them, intact pluripotent colonies are first lifted, induced to form EBs, and then grown in the presence of lineage specific morphogens and growth factors t

• Runx also controls the proliferation and neuronal differenti

  2018-11-08

  

  Runx1 also controls the proliferation and neuronal differentiation of certain neural progenitor cell populations. In embryonic olfactory bulb progenitor cells in vivo, as well as in cultures of either embryonic olfactory progenitor cells or embryonic cortical NSPCs, Runx1 increases cell proliferatio

• T-5224 The chronotropic responses of the hPSC CMs to various

  2018-11-08

  

  The chronotropic responses of the hPSC-CMs to various cardio-active drugs in our study are well in line with the published results (Mandel et al., 2012; Pillekamp et al., 2009; Pillekamp et al., 2012; Xu et al., 2002), in which the beating rates of CMs were increased in response to isoproterenol and

• br Resource table br Resource details Multiple endocrine neo

  2018-11-08

  

  Resource table Resource details Multiple endocrine neoplasia type 1 (MEN1) (also termed Wermer syndrome) is an autosomal dominant hereditary which is caused by mutations on the tumor suppressor gene MEN1. MEN1 is characterized by tumorigenesis mainly in endocrine organs including parathyroid g

• The approach for stem cell identification utilized herein is

  2018-11-08

  

  The approach for stem cell identification utilized herein is functional, based on the relative quiescence and thus label retention property of stem protease activated receptor within a mixed epithelial population. Long-term 5-bromo-2′-deoxyuridine (BrdU) retention has been previously used to label

• In this study we transplanted human

  2018-11-08

  

  In this study, we transplanted human iHeps into the livers of Gunn rats. Proliferation of the transplanted order ABT737 was induced by preconditioning a single liver lobe by hepatic X-irradiation (HIR). HIR enhances the engraftment of transplanted cells by transiently disrupting the sinusoidal endot

• There is now compelling evidence indicating

  2018-11-08

  

  There is now compelling evidence indicating that both the EMP and definitive programs derive from progenitors known as hemogenic endothelial order CT99021 (HECs) that display endothelial markers and are associated with the arterial vasculature (Bertrand et al., 2005; Boisset et al., 2010; Clarke et

• To elucidate whether the expression pattern of Zscan has

  2018-11-08

  

  To elucidate whether the expression pattern of Zscan4 has any correlation with ESC proliferation, we monitored Zscan4 activity at single cell level. Also to see whether the rejuvenation factor Zscan4 correlates with the fluctuating wave of ESC pluripotency (Figure S1), we monitored Zscan4 and the pl

• br Results br Discussion Extensive microarray datasets have

  2018-11-07

  

  Results Discussion Extensive microarray datasets have been published previously. The ImmGen consortium offers unique data that were generated by multiple groups following a unified and strict protocol. We have previously analyzed this dataset to reveal genes that are preferentially expressed i

• Our study found a link between screening and

  2018-11-07

  

  Our study found a link between screening and delay in seeking medical advice. Attending regular BC screening aid in the self-awareness process and helped women understand the seriousness of their condition, three women in our study had BC screening before and knew about BC, this knowledge prompted t

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